Bruce refuses to talk about his childhood or his past.
The one thing known is that he is a scientist, a doctor. All he wanted in life was to do good. He was hired by Stark Industries to work on gamma radiation, for medicine, only to discover that Obediah Stane was using his research to build weapons.
He set out to destroy all of his research refusing any of it to be used to destroy or hurt others, but Stane’s men cornered him and everything went to shit.
He escaped with his life, but ended up killing innocent people in the process. His guilt and anger with himself for not seeing what Stane was up to, had him ‘Hulk’ out. He learned quickly to calm himself down … but his own fears, guilt and anger became a viscous cycle.
He escaped Stane for a few years, not even taking the chance to get a hold of Tony Stark, even after he heard about his kidnapping.
He let his guard down once and ended up captured by Magneto.
A mutant set out to duplicate his ‘mutation’.
He didn’t have the heart to tell him it wasn’t one.
Bruce was rescued when the Vampires raided the lab, looking for one of theirs. Realizing he may finally find true help, he ended up working with them. It was during this time he was reunited with Tony.
He smirked when he found out that Tony kicked Stane out of Stark Industries, but was heartened by the fact Stane was a Vampire and still out there.
After the war with the Mutants, Bruce took Mal up on his offer to settle in Alaska, away from everyone, and the ability to work and find a cure. Tony made sure he was fully supplied with anything he needed.
He knows the two of them will have to talk, and tell their stories.
Bruce has settled in Alaska, finding it calming and relaxing. He’s made friends with Robert Neville and his Mate Jack. He’s discovered interestingly that Sam, the dog, is very tuned with his emotions, and if he starts to get to agitated the dog works to calm him down.
He’s still not sure if he can cure himself, but he’s determined to cut the cycle of rage.
Though his therapist Niles Crane sometimes drives him batshit, he’s very good at listening and suggesting ways to stay calm.
With the ‘Hulk’ in the background – it’s very unlikely Bruce can be Turned. At the moment, they aren’t willing to find out.